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Diosgenin Determination of Costus Speciosus Water Extract Using Hplc Method Image
Journal article

Diosgenin Determination of Costus Speciosus Water Extract Using Hplc Method

Effect of Diabetes Condition on Topical Treatment of Binahong Leaf Fraction in Wound Healing Process Image
Journal article

Effect of Diabetes Condition on Topical Treatment of Binahong Leaf Fraction in Wound Healing Process

Diosgenin Determination of Costus Speciosus Water Extract Using Hplc Method Image
Diosgenin Determination of Costus Speciosus Water Extract Using Hplc Method Image
Journal article

Diosgenin Determination of Costus Speciosus Water Extract Using Hplc Method

Effect of Diabetes Condition on Topical Treatment of Binahong Leaf Fraction in Wound Healing Process Image
Effect of Diabetes Condition on Topical Treatment of Binahong Leaf Fraction in Wound Healing Process Image
Journal article

Effect of Diabetes Condition on Topical Treatment of Binahong Leaf Fraction in Wound Healing Process

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Patient Knowledge and Rationality of Self\u002Dmedication in Three Pharmacies of Panyabungan City, Indonesia Image
Journal article

Patient Knowledge and Rationality of Self-medication in Three Pharmacies of Panyabungan City, Indonesia

Self-medication is a part of community effort to preserve their health. In practice, the self-medication can be a source of drug related problem because of lack of knowledge about drugs and their use. The aim of this study was to determine the level of knowledge and rationality of medicinal use self-medication. This study was using survey cross-sectional method. Total respondents (n=342) were involved this study of three pharmacies. Respondents were 18-60 years old and selected by consecutive sampling method. Data was collected by using a validated questionnaire. Data were analyzed by Chi-square test and Fisher test using Statistical Product and Servicer Solution (SPSS) version 17. The research showed that level knowledge of patients 20.5 % were good, 41.8% were medium, and 37.7% were low. Drug use self-medication was 59.4% rational and 40.6% irrational used. Based the result of Chi-square and Fisher test, educated and jobs can influence the level of knowledge, meanwhile rationality of self-medication use was not influenced by sociodemographic factor. Based on the research results obtained that majority level knowledge of patient was good classified. Irrational drug use on self medication reached 40.6%.
Formulasi Sediaan Nano Herbal Tempuyung (Sonchus Arvensis L.) Dalam Bentuk Self Nano\u002DEmulsifying Drug Delivery System (SNEDDS) Image
Journal article

Formulasi Sediaan Nano Herbal Tempuyung (Sonchus Arvensis L.) Dalam Bentuk Self Nano-Emulsifying Drug Delivery System (SNEDDS)

Tempuyung (Sonchus arvensis L.) merupakan tanaman asli Indonesia yang berhkasiat sebagai diuretik dan antioksidan. Untuk mendapatkan efek terapi yang optimal perlu inovasi untuk membuatnya menjadi sediaan nano herbal. Penelitian ini bertujuan membuat sediaan nano herbal tempuyung dalam bentuk Self Nano-Emulsifying Drug Delivery System (SNEDDS). Kandungan zat aktif tempuyung diekstraksi dengan etanol dan berikut diuapkan pelarutnya untuk mendapatkan ekstrak kental. Ekstrak yang diperoleh distandarisasi menurut Farmakope Herbal Indonesia. Berikutnya dibuat SNEDDS tempuyung dengan menggunakan minyak Capryol-90, surfaktan tween 20 dan ko-surfaktan PEG 400. SNEDDS yang diperoleh dikarakterisasi meliputi ukuran partikel dan zeta potensial. Dari ekstraksi diperoleh ekstrak kental sebanyak 77,52 g. Hasil ini telah memenuhi syarat jika dibandingkan dengan Farmakope Herbal yang menyebutkan perolehan rendemen ekstrak kental daun tempuyung adalah tidak kurang dari 7,5%. Formulasi tempuyung dalam bentuk sediaan SNEDDS diperoleh suatu nanoemulsi yang jernih dengan ukuran partikel 16,2 ± 1,06 nm dan nilai zeta potensial -37,48±0,74 mV. Dapat disimpulkan bahwa ekstrak tempuyung menghasilkan suatu nano herbal dalam bentuk sediaan SNEDDS.
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Analysis on Protein Profile and Amino Acid of Edible Bird\u0027s Nest (Collocalia Fuchiphaga) From Painan Image
Journal article

Analysis on Protein Profile and Amino Acid of Edible Bird's Nest (Collocalia Fuchiphaga) From Painan

This study was aimed to analyze protein profile and amino acid composition of bird nest from Painan, Pesisir Selatan Distric, West Sumatra. Protein analysis was performed by Sodium Dodecyl Sulphate Polyacrilamide Gel Electrophoresis (SDS-PAGE), meanwhile High Performance Liquid Chromatography (HPLC) was used for analysis of amino acid. Analysis on water extract of bird nest by SDS-PAGE showed six bands which correspond to molecular protein which had molecular weight of 147.2; 142.6; 133.4; 73.3; 66.2; and 37.7 kDa, respectively. HPLC analysis demonstrated that bird nest was composed of 16 amino acids. Seven of them were essential amino acids; histidine (2.31%), leucine (3.84%), threonine (3.82%), valine (3.93%), methionine (0.48%), isoleucine (1.80%), phenylalanine (4.49%), and nine of them were non-essential amino acids; serine (4.56%), aspartic acid (4.48%), arginine (3.93%), lysine (2.34%), proline (3.64%), glutamic acid (3.65%), glycine (1.87%), alanine (1.31%), and tyrosine (3.92%). Serine was the highest percentage of amino acid in the bird nest (4.56%), followed by phenylalanine (4.49%) and aspartic acid (4.48%). The study also showed that composition of amino acid in this bird nest was slightly different with composition of amino acid in bird nest from other area.
Journal article

Identification of Human Papillomavirus Type 18 (HPV 18) E7 Gene From Cervical Cancer Patients

Identification of Human Papillomavirus Type 18 (HPV 18) E7 Gene From Cervical Cancer Patients Image
Journal article

The Effectiveness of Liposome Delivery System of Catechin as Antioxidant

The Effectiveness of Liposome Delivery System of Catechin as Antioxidant Image
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