Development in agricultural mechanization is characterized by the increasing use of agricultural machinery and equipments. It can be seen from sugarcane harvesting process which machinery is used instead of manual equipment. In term of using the harvesting machinery operated by human, the principle of ergonomic should be applied to fulfill the goal of work productivity and ensure occupational health and safety. It is because, during its operation, there will be a potential hazard, caused by noise and vibration, to workers and the environment. This research was aimed to analyze the noise and vibration level of Saccof Harvester during its employment. It was expected that the time limit for the optimal use of the machine can be determined based on the available standard. Furthermore, the method to reduce the negative impacts of noise and vibration can also be identified. According to the research, it was revealed that the noise and vibration level which was received by operator exceeded the ambient level. Consequently, there is necessity to control of noise and vibration on both the source (harvesting machinery) and the receiver (operator).