Monthly, 23.2% of new patients in hospital had an indwelling urinary catheter, and 80% of them had urinary tract infections. Data showed that this infection was contributed to 32% of death in nosocomial infection cases. Using the periurethral cleaning solution before the insertion of indwelling catheter to reduce urinary tract infections are still debated. This literature review used some databases such as CINAHL, proquest and google scholar that published between 1995 and 2013. Key words included catheterization, indwelling urinary catheter, bacteriuria, meatal or periurethral cleaning, urinary tract infection, and nursing. This study reviewed 25 appropriate literatures. The solution were tap water, sterile water, antiseptic solution, and normal saline. Statistically, there was no differences of incidences of urinary tract infection when tap water solution compared with povidone-iodine or chlorhexidine 0.1% as well the use of sterile water compared with povidone-iodine or chlorhexidine gluconate 10% or 0.05%, water and soap, skin cleansing foam, povidone iodine, and normal saline. Sterile water is an inexpensive hypotonic solution and does not irritate the skin. Normal saline is also less expensive and less irritating to the skin. Antiseptic solution is quite expensive, can irritate the skin, and have an allergic or toxic side effects. Soap has little value as an antiseptic and relatively inexpensive. Tap water, sterile water, antiseptic solution, normal saline, and water and soap are some solutions that can be us as periuretral cleaning solution. Further study related to the USAge of steril water or normal saline is needed.