Climate change happened and resulted in adverse effect of our life on the earth's surface. Droughts, floods, or rob, heatwaves, and hurricanes happened recently of incident that might be caused by climate change. In the agricultural sector, these conditions will lead to reduction of yields significantly, in turn disrupt the national food security and reduce foreign exchange. Major factor that may induce climate change is the increased greenhouse gas emissions primarily CO2 in air, generated by human activity (anthropogenic). To reduce emissions of CO2 gas, Government of Indonesia has launched the National Action Plan for Reducing Emissions of Greenhouse Gases (RAN-GRK) through Presidential Decree No. 61 of 2011. One of the main activity is the planting of 105,200 ha of rubber trees. Ecological role of the rubber plant is an sequestration CO2 from the air. Moreover, rubber yielded may be converted into biodiesel fuel having CO2 content being lower than diesel oil in otherwords, rubber plant has an important role in reducing of incidences of climate change (mitigation). The amount of CO2 is sequestrated by rubber plant varies depending on the age of the plant, crop conditions, soil fertility and technical cultivation applied. Average of carbon stock of those rubber plants cultivated traditionally was 19.8 ton C / ha, while those superior clone ones was 42.4 ton C/ha. The amount of CO2 gas sequestrated by rubber in Indonesia reached of 291.16 Mton CO2e. Potentially biodiesel production developed from the RSO in Indonesia reached 424,460 ton, blending of diesel oil and biodiesel from RSO able to reduce CO2 emissions of 40.14%.