Cardiovascular disease causes 8.6 million deaths of women every year, which is the major cause of death by one-third of all deaths of women in the world. Half of all deaths of women older than 50 years old is caused by cardiovascular and stroke diseases. This study aimed to analyze risk factors related to coronary heart disease among women aged older than 45 years at Dody Sarjoto Makassar Air Force Hospital 2016. The total of sample was 76 consisting of 64 cases of coronary heart disease and 12 non-coronary heart disease. Determination of sample used purposive sampling. Primary data were obtained through interview to respondents using questionnaire and direct interview. Data were analyzed by using contingency correlation coefficient (Exp (B)) test to identify significant relation between dependent and independent variables. Results found were hypertension (Exp (B) = 0.309), obesity (Exp (B) = 0.140), diabetes mellitus (Exp (B) = 0.164) and dyslipidemia (Exp (B) = 0.185), as proven having relation with coronary heart disease among women aged older than 45 years, and the factor which had the most significant relation was dyslipidemia.