White shrimp Litopenaeus vannamei culture in floating cage in the sea have very good prospect to be expanded. This culture requires good quality and quantity of juveniles. The juveniles can be obtained from intensive system of nursery. However, this system has some limitations because the high stocking density and amount of feed increases. Unconsumed feed and shrimp metabolite excretion accumulated in the water, this caused the concentration of nitrogen compounds, especially ammonia in the water increased. Currently, Bio-flocs technology (BFT) was developed to reduce waste shrimp or fish farming activities. The purpose of this research was nursery of white shrimp (L. vannamei) with bio-flocs technology to increase the growth and efficiency of feed. The design the research was completely randomized design, consisted of two experimental treatments with three replications. The result of this research showed that shrimps fed in BFT system (B) had growth (9,85%) and efficiency of feed (37,33%) higher than that in the control (K). The nursery of white shrimp (L. vannamei) with bio-floc technology resulted in significantly higher growth and feed efficiency than the control (P<0.05).