Macrozoobenthic is one of the organisms whose existence is widely present in the seagrass ecosystem. This study aimed to analyze the differences in individual abundance and macrozoobenthic species in full-moons and neap, to see the correlation of macrozoobenthic abundance with seagrass closure, and to know the contribution of macrozoobenthic species to seagrass habitat. The study was conducted in Panggang Island with 3 makrozoobenthic observation stations in the seagrass ecosystem at March and April 2016. Makrozoobenthic data collection in seagrass systematically using 1x1 m quadrant transect method and 10 cm diameter corer for infauna. Analyzing the density, seagrass cover and macrozoobenthic abundance. Analysis statistics of macrozoobenthic abundance data using ANOVA test, macrozoobenthic density correlation with seagrass cover using simple linear regression and contribution of species on full moon and neap using SIMPER analysis. The result of this research shows that there is no real difference of macrozoobenthic individual abundance in full moon and neap. While the species obtained significant significant differences. The SIMPER analysis shows the highest contribution of macrozoobenthic species in each station on the full moon and the neap is the species of Cerithium salebrosum. Conclusions The density of macrozoobenthic species shows a marked difference in the full moon and the neap, but not the individual abundance.