Many Indonesians still use Thinner as paint cleaner solution. Thinner is a compound of petroleum. Petroleum is a non-renewable natural resource. Under these conditions, alternatives are needed that can be used either to replace or reduce the use of thinner. The alternative to use chemicals is caustic soda (NaOH). The criterion and sub-criteria which is to know the priority of use in choosing cleaning fluid of paint chemical obtained by conducting interview with user of caustic and thinner liquid to clean paint. The result of the interview is processed into questionnaires and calculated using ANP obtained 5 criteria (Economics, Environment, Technical, Concentration and Time) and 10 sub- criteria. Decision-making alternative to thinner cleaning paint alternator using ANP method gives higher priority value of caustic soda that is 0.67617 or 67.6% compared with thinner priority value of 0.392383 or 39.3%. So caustic soda is an alternative liquid to replace the thinner as a cleaning fluid. The optimal concentration of liquid caustic soda (NaOH) is 187.5 M with a mixture of 150 grams of water with a volume of water / aquades of 20 ml resulting in a 10-minute peel time.