Introduction: The research was aimed to obtain the dosage of NASA liquid organic fertilizer (LOF), goat manure (GM) and combinations are appropriate to support the growth and yield of wax apple. Materials and Methods: This research was conducted at Payaroba Street, Binjai City, North Sumatra Province from Juni to December 2018. This research used the randomized block design factorial within the first factor was NASA LOF (C0= 0 ml.l-1; C1= 1 ml.l-1; C2= 2 ml.l-1; C3= 3 ml.l-1 in water), and the second factor was GM (K0= 0 kg.polybag-1; K1= 0.5 kg.polybag-1; K2= 1.0 kg.polybag-1; K3= 1.5 kg.polybag-1) using three replications. Parameters were analyzed using the ANOVA and continued with the least significance different at rate of 5%. Results: GM significantly increased the plant height, stem diameter, number of flower, and fruit weight of wax apple along with increasing doses until 1.5 kg.polybag-1 of 11.76%; 16.70%; 12.90%; and 7.55% respectively, and accelerating the flowering of 2.98 days compared to un-treated. The application of NASA LOF significantly increased the plant height, stem diameter, and number of flower by wax apple along with increasing doses until 3 ml.l-1 water by 7.51%; 46.61%; and 11.04%, and accelerating the flowering of 5.16 days compared to un-treated. The combination of NASA LOF at 2 ml.l-1 water and GM at 1.5 kg.polybag-1 significantly increased the stem diameter by 52.89% compared to the control combination. However, it did not show a significant effect on plant height, flowering, number of flower, and fruit weight of wax apple.