The use of rice varieties tolerant to iron toxicity is an efficient way to deal with low rice production in iron toxicity areas. The varietal improvement activities consisted of evaluation, screening of rice germplasm, bulk population of crossed materials, and introduction. Varietal screening was conducted by direct selection at the iron toxicity areas of +200 ppm Fe content at Tamanbogo, Lampung. Anther culture would speed up breeding activities due to the availability of genetic resources tolerant to Al toxicity which were having high regeneration and callus induction. The character of Fe tolerance was controlled by two or more dominant genes which were epistatic and duplicate genes, additive, dominant and non allelic interaction genes. Selection for Fe tolerance at advanced generation could increase degree of homozygotes, lead to more tolerant genotypes and increase selection effectiveness. From bulk population had been selected tolerant lines in the early generation were some lines of IR64 progeny, promising lines from crossings of introduced IRRI varieties and local varieties. Nine rice varieties released for tidal swamps areas. More than 100 accesions of rice germplasm tolerant to Fe toxicity had been evaluated.