Screening of sweetpotato germplasm resistant to weevil was done in Indonesian Agricultural Biotechnology and Genetic Resources Research Institute Bank Gene Laboratory during October-November 2002. Fifty accessions of tuber root were evaluated. Three tuber roots were infested by five pairs of Cylas formicarius Fabr. for each accession with three replications. Three days after infestation (dai), the insects were move out from its container and 30 dai the resistance was scored. The results showed that only one accession Yoban (2%) resistant and nine accessions (18%) were moderately resistant, 24 accession were moderate susceptible (48%), and 16 accessions were susceptible (32%). Yoban variety has potential to be used as parent material in breeding of sweet potato for resistant to weevil.