Stroke is a disease that is a problem in the world, especially ischemic stroke. Stroke is a disease caused by circulatory disorders of the brain that are affected by several risk factors can not be changed such as age and gender. While the risk factors that can be changed such as hypertension, diabetes, dyslipidemia and jobs. Effective measures to reduce the incidence of stroke is by controlling risk factors that can be changed. This study aims to determine the relationship characteristics and hypertension with ischemic stroke events in hospitals Ngimbang Lamongan Year 2016. This study was analytic observational with case control design.Sample cases is ischemic stroke patients, while the control sample is non ischemic stroke, each as much as 44 respondents. The sampling technique by using simple random sampling. Collecting data use secondary data by viewing the data records. The statistical test used was chi square test. Research that shows there is a significant relationship with the occurrence of ischemic stroke were age (p = 0,015; OR = 3,286; 95% CI 1,332 to 8,107), gender (p = 0,001; OR = 4.765; 95% CI 1,912 to 11,875 ), employment status (p = 0.001; OR = 4.667; 95%CI 1,890 to 1,526), and hypertension (p = 0,000; OR = 129,000; 95% CI 15,848 to 1050,034). The conclusion from this study was there are a relationship between age, gender, employment status and hypertension with ischemic stroke events in hospitals Ngimbang Lamongan 2016.