
Ferry Sandra, Janti Sudiono, Pretty Trisfilha, Deviyanti Pratiwi
BACKGROUND: Alpinia galanga (A. galanga) was reported as a potential medicinal source due to its wide effect. A. galanga rhizome crude extract (ARCE) was reported to have high cytotoxic effect in canc...

Yusrawati Yusrawati, Dyka Aidina, Eti Yerizel
BACKGROUND: According to the theory of endothelial dysfunction, the pathogenesis of preeclampsia is associated with the imbalance of angiogenic and anti-angiogenic factors. Transforming growth factor-...

Djanggan Sargowo, Olivia Handayani
BACKGROUND: The association between elevated triglycerides and cardiovascular risk has been extensively studied. The elevated level of triglycerides occurs through abnormalities in hepatic very low-de...

Octaviani Octaviani, Agus Rahardjo, Untung Alifianto, Setya Anton
BACKGROUND: Peritoneal adhesion is a side effect of abdominal surgery that often occurs. Many efforts were made in abdominal surgery to prevent or minimize the occurrence of this adhesion. One way to ...

Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya
BACKGROUND: Recently established genome editing technologies will open new avenues for biological research and development. Human genome editing is a powerful tool which offers great scientific and th...

Isabelle Deli Lestadi, Nurjati Chaerani Siregar, Puspita Eka Wuyung
BACKGROUND: Plasma cell neoplasm (PCN) is a neoplastic plasma cell proliferation which includes solitary bone plasmacytoma (SBP), extramedullary plasmacytoma (EMP) and multiple myeloma (MM). Bartl cla...

Idar Mappangara, Magma Purnawan Putra, Khalid Saleh
BACKGROUND: Many studies showed the association between peripheral artery disease (PAD) and coronary artery disease (CAD). The anklebrachial index (ABI) was a simple, noninvasive, and not expensive te...

Siska Mayasari Lubis, Miswar Fattah, Harun Alrasyid Damanik, Jose Rizal Latief Batubara
BACKGROUND: Childhood obesity is associated with the risk of adult obesity and obesity-related chronic disease. The fat mass and obesity-associated gene (FTO) rs9939609 variant are of particular inter...

Arundina Sanyoto, Ketut Suega, Losen Adnyana, I. Made Bakta
BaCKGROUND: Diagnosing iron deficiency anemia (IDA) is easy, but also can be complicated in condition with inflammation. A new modality for diagnostic which isn't influenced with inflammation is neede...

Djanggan Sargowo, Titin Andri Wihastuti, Cathrine Theodora Sukotjo, Prasanti Mahesa Anjani, Olivia Handayani
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, Liemena Harold Adrian
BACKGROUND: Type 2 Diabetes Mellitus (DM) is one of dominant factors in cardiovascular deaths and induces endothelial dysfunction. A definite sign of endothelial dysfunction is foam cells formation de...

Ferry Sandra, Karina Febriani Hudono, Amelia Astriani Putri, Chantika Amardhia Paramita Putri
BACKGROUND: Caffeic acid has been shown to induce apoptosis in MG63 osteosarcoma cells. Along with the apoptotic induction, caffeic acid was shown to activate caspase-8, -9 and -3. However, the role o...

Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya
BACKGROUND: The number of elderly population in the world keep increasing. In their advanced ages, many elderly face years of disability because of multiple chronic diseases, frailty, making them lost...

Yenny Surjawan, Hwee Lian Tan, Rahajuningsih Dharma Setiabudy, Wiwik Rositawati
BACKGROUND: The mutation spectrums of hemoglobinopathy are different among populations that yield a different result of erythrocyte indices. Calculation of erythrocyte indices with some formula has be...

Asri Hendrawati
BACKGROUND: Increasing free radicals and oxidative stress due to chronic hyperglycemia in type-2 diabetes mellitus (DM) promotes the activity of endogenic antioxidative genes. Nuclear factor erythroid...

Ferry Sandra, Janti Sudiono, Ciptadhi Tri Oka Binartha, Angliana Chouw, Melanie Sadono Djamil
BACKGROUND: Dental pulp stem cell (DPSC) and periodontal ligament stem cell (PDLSC) have been suggested as valuable seed cells for bone engineering, suggesting that both stem cells are potential osteo...

Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya
BACKGROUND: The introduction of mechanism based targeted therapies to treat human cancers has been pledge as one of the results of three decades of remarkable progress of research into the mechanisms ...

Djaja Rusmana, Roro Wahyudianingsih, Mariska Elisabeth, Balqis Balqis, Maesaroh Maesaroh
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, Wahyu Widowati
BACKGROUND: Normal metabolism of oxygen and exogenous factors constantly generate free radicals which could be harmful to the human body. Human need antioxidants to provide protection against free rad...

Arash Payehdar, Ebrahim Hosseini, Davood Mehrabani, Mohsen Forouzanfar
BACKGROUND: Busulfan, a chemotherapeutic drug, is an alkylating antineoplastic agent that belongs to the class of alkyl sulfonates and has some side effects on fertility. This research was aimed to in...

Sunarno Sunarno, Yuanita Mulyastuti, Nelly Puspandari, Kambang Sariadji
BACKGROUND: dtxR gene is a global regulator that can be used as a marker for detection of Corynebacterium diphtheriae (C. diphtheriae) and it is also a representative tool for mapping purpose (molecul...

Samad Javadi, Hojjatallah Alaei, Ebrahim Hosseini, Mohammad Amin Edalatmanesh
BACKGROUND: The prelimbic area (PL) of the prefrontal cortex is susceptible to abnormal developmental stimuli that raises the risk of addiction. Glutamate receptors play a key role in opiate reinforce...