Intorduction: This study is based on preliminary question that six among ten of students who attend block learning symptoms experience the symptoms of stress. This study is focused on to identify how often the students experience the symptoms of stress and which one between them the most or less frequently occurs. Method: The study design is using descriptive quantitative method, total sampling of 35 level 3 nursing students in Diploma 3 program who attend learning block system. Instrument is using a questionnaire that content 16 symptoms of stress. Data is arranged and analyzed by using mean and deviation standard value. Result: The result shows that most of the student are often manifesting the symptoms of stress with the mean value of 3,09 and standard deviation 1,06. The most frequently symptom is difficult to concentrate with mean value3,34 and deviation standard 0,906. The less frequently is crying with mean value 2,66 and deviationstandard1,887. Discussion: this study is look different with previous study in which the most frequently symptoms was crying while in this study crying was less frequent symptoms occurs.