Introduction: Basil leaves (Ocinum Basilicum) is a medicinal plant in Indonesia, which is often used as a traditional medicine. Basil leaves containing active compound flavonoids and magnesium which can lower blood pressure. Objective: This study aimed to determine the differences between the mean blood pressure before and after the infusion of basil leaves in women with hypertension Sadium one in Karyawangi the village of West Bandung regency.Methods: The method used was pre experiment with one group pretest-posttest design. The subjects used were adult women aged 35-60 years with a one-stage hypertensive blood pressure values of 140 / 90-159 / 99 mmHg. A sample of 20 adult women with hypertension stage one chosen by consecutive sampling. Interventions performed for 6 days. The statistical test used was hypothesis testing using t-test two parties. Results: The average value of blood pressure before intervention in the amount of 149.5 / 93.9 mmHg and the average value after intervention in the amount of 136.6 / 86.6 mmHg. The difference in systolic blood pressure was 12.9 mmHg and diastolic blood pressure by 7.3 mmHg. Discussion: There was an effect of basil infuse on blood pressure. Infuse basil leaves can be used as an alternative therapy to treat high blood pressure.