This study was conducted to determine the effect of liquidity and solvency on profitability in the food and beverage sub-sector listed in Indonesia Stock Exchange period 2013 until 2016 because that often happens company can not balance that where a position of liquidity and solvabilities not adequate due to company orientation which always the pursuit of profit without compensating for the management of the aspect of the ability to pay its obligations or because the company is too concerned about liquidity and solvency so that it neglects its profitability aspect.This study uses multiple regression analysis tools with significance 0,050 and data analysis using spss application. The variable for liquidity is measured by using current ratio, solvency is measured by dept to equity ratio while profitability is measured by net profit margin. Sampling method used is purposive sumpling method.The result of research partially show that liquidity have significant effect and have positive correlation to profitability, whereas solvability also have significant effect to profitability and have a positive correlation. Simultaneously, liquidity and solvency have a significant effect on profitability.The conclusions of this study suggest that the three proposed hypotheses are proved or the three hypotheses accepted. This means that the company's ability to meet its short-term and long-term debt obligations affects the company's profit. The higher the pay rate then followed by the increasing profit achieved by the company.