The article considers about an oxadixyl complication with water-soluble polymers - polyacrylic and polymethacrylic acid. The main methods for studying the interaction of polymers used oxadixyl viscometry, potentiometry, conductivity, and ultracentrifugation, ultraviolet and infrared spectroscopy. The influence of different factors on the process of complication detecting that binding oxadixyl polymers leads to structing macromolecular chains of the formation of hydrogen bonds