Rheumatic fever is a systemic inflammatory disease of the connective tissue, the process of which is located in the cardiovascular system, developing in connection with group A -hemolytic streptococcal (ABGS) infection, mainly in children (7- 15 years) and occurs when there is a tendency in young people. V.D. Belyakov's epidemiological analysis shows that ABGS infection appeared at the end of the 20th century and is still increasing. His analysis made the following prediction: “We are entering the 21st century, in the first half of which, according to the laws of life of streptococcal infection, as in the beginning of the twentieth century, it must show its power. In the near future, we will face a highly virulent, aggressive ABGS infection, just like in the early 20th century. ” This prognosis suggests that with the increase in epidemic “outbreaks” of SARS, the incidence of ABGS infection in the United States and Western Europe is increasing, even fatal.