Antioxidants are one of the free-radical scavengers. Methanol extract of rambutan peel containing phenolic compounds such as acids ellagat, corilagin and geraniin potential as antioxidants. Facial cosmetics are available in a variety of dosage forms, one of which shaped peel-off mask gel. The purpose of this study to determine the antioxidant activity and irritation test preparation gel mask methanol extract of rambutan peel. Research stage begins with the search for materials, manufacturing of rambutan peel extracts, extracts DPPH test, preparation of a peel-off mask gell, DPPH test preparation, and irritation test. The results showed the extract inhibition concentration is 6.6771 µg / mL; inhibition concentration of gel peel-off mask at F0, F1, F2, F3 where F0 does not contain extracts, F1containing 50 mg of extract, F2 = 150 mg extract; F3 = 250 results inhibition concentration obtained mg ektrask respectively 8.867; 6.655; 6.786; 6.598 µg / mL. Skin irritation test preparation rambutan mask to F0 are erythema in rabbits 1 and 2 at the 24th hour and 48 while in rabbits 3 at the 24th hour. For F1 and F2 erythema occurred at the 24th hour and 48 for rabbits 1, all hours of the rabbit 2 and the 24th hour in rabbits 3. Eritema happened in F3 found in rabbits 2 at the 24th hour, 48 and 72. edema does not occur in any formula at all rabbits.