Cu-ZnO catalyst in this study made for the reaction of glycerol to propylene glycol hidrogenolysis with sol gel process fromacetate salts. pH is an important parameter in sol gel process in the synthesis of Cu-ZnO nanocatalyst. pH ajustment of the sol influencing the morphology and structure of Cu-ZnO catalyst, seen from the characterization performed by X-Ray Diffractometer (XRD) and Scanning ElectronMicroscope (SEM). Diffraction spectra showed that the particle size of Cu-ZnO material is strongly influenced by the preparation. Cu-ZnO materials prepared at pH 7 and 8 showed a stong peak, mean the peak is broadening on Cu-ZnO prepared at pH 9. SEM-EDS of Cu and Zn ratios is different, which at pH 7 and 8, the ratio of Cu greater than Zn, while at pH 9, the ratio of Zn is higher than Cu which shows the interaction that changes the structure of the material in the presence of pH treatment. Confirmed by GC-MS analysis, at pH 7 and 8 the structure of Cu is in the core material and surrounded by Zn, and vice versa at pH 9 the structure of Zn in the nucleus and surrounded by Cu.