Formulations Slow Release Tablet Diclofenac Sodium Using Starch From Saba Banana (Musa Balbisiana L)

Deni Anggraini • Anita Lukman • Ria Mulyani
Journal article Jurnal Sains Farmasi dan Klinis • 2016

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(Bahasa Indonesia, 6 pages)

Abstract

The formulation of slow release tablet of diclofenac sodium using a matrix of starch from saba banana and sodium carboxyl methyl cellulose as a comparison has been done. The purpose of this study was to determine whether the slow-release preparations produced with starch from saba banana met the requirements of slow-release tablet . The dissolution test results show the formula I (starch of saba banana) was dissolved 110.24 %, formula II ( sodium carboxyl methyl cellulose ) was disolved 39.04 % within 8 hours. The dissolution test results showed that starch of saba banana did not meet the requirements as a matrix because it could not not reduce the rate of dissolution . The kinetics of the release of active substances from the matrix between the two formulas followed Higuchi equation .

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Jurnal Sains Farmasi dan Klinis

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