Introduction: Circumcision is treatment which needed preparation, one of them is anesthesia treatment. As long as circumcision treatment, pain will be feel only at the time anesthesia circumcision injection. Nurses often have difficult to make action procedure of anesthesia circumcision injection because children often refuse to procedures which will occurs pain feeling. One of non pharmacology managements to reduce pain on children by giving children breath is playing with a blow vane. Objective: The purpose of study to identify the effect of slow deep breathing therapy by playing with a blow vane to pain intensity on children with anesthesia circumcision injection. Methods: This study used a quasi experimental design by control group post test. Populations were all children who had been performed anesthesia circumcision injection in Kencana Medika Circumcision Clinic. Used 36 samples consist of 18 samples were in intervention and control group. Pain response was measured by Faces Pain Rating Scale. Result: The results were analyzed using the Mann-Whitney showed there are significant differencebetweenthe interventionandcontrolgroups with ap-value of0.000 and α £ 0.05. The conclusioniseffect of slow deep breathing theraphy by playing with a blow vane to pain intensity on children with anesthesia circumcision injection.