Pelus river is one of the macro drainage system with a total length of ± 19.809 km. Determination of the status of water quality in the river Pelus necessary to know how big the blackened conditions experienced by Pelus river. This study aimed to analyze the factors that cause changes in the concentration of turbidity, DO, pH, Feral Coliform, TDS, BOD, nitrate, total phosphate, and the temperature in pollution control efforts in the future. Status of water quality in Pelus river used projections discharge as tools in the determination of status of water quality. This happens because the study occurred during the rainy season, where the concentration does not show the actual values. Pelus river water quality assessment carried out by using NSF-IKA, the results indicate sampling points 1 and 2 gain medium polluted category. Settlement activity to provide input to the highest organic pollution Pelus river.