Kadar Leptin sebagai Petanda Diabetes pada Individu dengan Diabetes dan Toleransi Glukosa Terganggu

Uly Alfi Nikmah • Frans Dany
Journal article Indonesian Bulletin of Health Research • 2017

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(Bahasa Indonesia, 8 pages)


Leptin is an adipocitokin hormone, produced by adipose tissue that is associated with the increasing of type 2 diabetic risk. Uncontrol impaired glucose tolerance (IGT)in a person has a high risk of being diabetics person. The aim of the research is to measure leptin level in an individu with diabetes mellitus (DM) and IGT in the year 2011 and 2013 and also to compare the leptin level with their lifestyle. Methods of the research are using ELISA technique and analyze the lifestyle based on the public health data. The results show that leptin level in the diabetics person is equivalent with impaired glucose tolerance person, and leptin level between groups is not significantly different in 2011 and 2013. The odds ratio of smoke behavior shows no correlation with leptin level, but thebody mass index (BMI)-risk on DM and IGT person shows 2.3 times than normal. Exercise habits on diabetic and IGT persons show that their leptin level is of 1.22 times lower, and the normal persons' leptin level is of 1.5 times lower than untreated persons with exercise. The result proves that exercises slightly decrease leptin level and also decrease the diabetes risk.




Indonesian Bulletin of Health Research

Buletin Penelitian Kesehatan (Indonesian Bulletin of Health Research) is a quarterly, open access... see more