Background: Muyu Tribes have an open mind toward modernization, while still holding fast to some beliefs that often collide with each other, not to mentional so the case in the original Muyu health workers. For health workers who came from the tribe Muyu, in daily life, it seems as if stuck on the pull two poles of different beliefs, and even sometimes the opposite.Medical concepts are studied and are believed to be a health worker was overlap and collide with the belief in the concept as part of the cultural tradition of his tribe. This study was conducted to explore in depth the pull of tradition surrounding the Muyu health workers. Methods: This research is a case study carried out in depth on indigenous health workers Muyutribe. This ethnography research was conducted in Mindiptana, District Digoel. Data collection was performed by means of participant observation, in-depth interviews and document searches. Result: The research results showed the infl uence of western and migrants in some ways helped change the mindset or perspective of health workers to be able to receivethe pattern rationalistic offered. But within certain limits if health workers are stuck in the old tradition of Muyu who tend to be irrational and mystical. Conclusion: Empirical fact that their tradition Muyu Tribe (indigenous health workers Tribe Muyu) believe, they often receive repetitive, making them not to circumvent these beliefs. Although, rationalistic culture completely different they have learned indifferent practice. Recommendation: Appropriate supervision can be a task thatshould be done by health personnel.