A clinical trial have been conducted during April 1997 to March 1998 in Surabaya. This study tested the effectiveness of tradisional medicine for treating vaginal discharge problem (Papaniculoan test) among woman. The traditional medicine consist of three medical plants (Piucheae indicae folium, Curcumae domesticae rhizoma and Granati fructus contex) which were k nown as anti macro organism 35 married women using oral pill have been evaluated to see the respond of the treatment. The result of the study showed that the traditional medicine was not effective for treating purulent inframation caused by bacteria. It was also not effective to kill trichomonas and fungi. The patient of non spesific inflamation (Pap test) have been cured by traditional medicine. This treatment did not damage the liver and kidney function seen by blood examination (SGOT, SGPT, BUN, Creatinin). This study concluded that the traditional medicine was not effective to cure vaginal diagnosed as purulent inflamation, trichomonas and fungi (Pap test), but it supposed to be suggested to use in the first step of treatment by the women themselves before they seek the medical treatment. It was safe for liver and kidney in the shorterm USAge.