Irrational use of drugs is still a problem in Indonesia. Therefore since 1983 the National Drug Policy (KONAS) has been develop general drug policy participating by all pharmacy players in Indonesia. To overcome the problems of irrational drug use, it is important to determine problems to develop appropriate and effective strategies. There are some indicators could be used to find out levels of rationa/irrational drug use in various health facilities, as one of them is prescribing indicator. This study aimed to determine levels of drug use at 6 (six) dispensatories in Bandung, Surabaya and Makassar cities by counting prescribing indicators. Data were selected from a research of the KONAS conducted in 2005 by center of Research and Development for Pharmacy and Traditional Medicine. Data were from 30 prescriptions in each dispensatory retrospectively from the day of survey. Results showed that the average number of drugs prescribed was 2.66%, the percentage of patients receiving injections was 8.89%, the percentage of patients receiving antibiotics was 45%, the percentage of drugs prescribed by generic name was 20.65% and the percentage of drugs prescribed in accordance to the National Essential Drugs List (DOEN) was 33.43%. In comparasion to the previous available data, it could be assumed there were better rational uses of drugs as shown in the average number of drugs prescribed and percentage of patients receiving injection. The contvary conditions were for the percentage of patients receiving antibiotics, the percentage of drugs prescribed by generic names and percentage of drugs prescribed in accordance to the National Essential Drugs List. It recommends to provide continued information on the rational drug use in accordance to, KONAS, DOEN and socialization to private sectors such as dispensatories.