The Health development targets are to accelerate the decrease of Maternal Mortality Rate (MMR) and Infant MortalityRate (IMR). In South Kalimantan Province since 1997 to 2000, some area, received Mothercare Programe trials, but the MMR and IMR remain so high. This study aimed to analyze policies issued by South Kalimantan Province in efforts to decrease the MMR and IMR, because the MMR and IMR are still high enough in comparasion to other provinces. It wasa descriptive study that retrospectively analyzed policies issued in the past and are still in use. Results showed almost all policies on health in 5 (five) Districts in South Kalimantan Province were based on the national policies. The policies issued by the District Governments that have a direct association to decrease the MMR and IMR in year 1997 were the District Government Decision Letter on Safe Motherhood (GSI/Gerakan Sayang lbu) with all the activities. The strategy on Making Pregnancy Safer (MPS) has not been conducted in all study areas because the information was j ust received in 2004. The alternative policies recommended in efforts to decrease the MMR and IMR are 1. It needs a sustainable program in the internal of health sector in which the Making Pregnancy Safer (MPS) could be used as basis of integrated efforts to decrease the MMR and IMR, 2. Because Safe Motherhood is well known in the community so it should be integrated to the MPS, 3. Data information should function more accurately, especially the MMR and IMR to be used for policies.