In the preliminary study conducted at Midwife Practice Mandiri Atik there are 30 (75%) Primigravida said not knowing what to do in the face of labor because what will be passed is first experience, so need to be given health education about pregnancy as stock in facing childbirth. The purpose of this study to determine the effect of health education on pregnancy to the level of knowledge of primigravida trimester III in the face of childbirth in Midwife Practice Mandiri Atik. The research method used is quasi experiment type with One Group Pre-test and Post-test design. Samples of primigravida trimester III research were 36 respondents. The result of this research is that the knowledge of the respondent before the health education is 73,52 and after the health education equal to 83,60 with tcount > ttable (-8,501> -2,042) or p-value <α (0,000 <0,05) then H0 Rejected and Ha accepted. This means there is an effect of providing health education on pregnancy to the level of knowledge in primigravida in the face of birth in the Midwife Practice Mandiri Atik.