Currently, obesity is considered an epidemic due to the disruptions it causes to health, highlighting the incensement in cardiovascular diseases associated with cholesterol and low-density lipoprotein (LDL) high concentrations. However, cholesterol is also involved in various metabolic and structural functions vital to human biology. This homeostasis can be modified by external factors such as medications or by internal factors such as diseases or metabolic changes generated by the type of diet at which each person is exposed.In this sense, the research points to the knowledge of functional foods, which provide beneficial health effects and prevent the risk of disease. It has been reported that hypocholesterolemic type bioactive peptides obtained by enzymatic hydrolysis of various seeds such as soybeans, rice and sunflower. A similar effect is observed with unsaturated fatty acids, which have antithrombotic and antiarrhythmic effects, prevent atherosclerosis, contribute to decrease blood pressure and reduce the concentration of triglycerides, total cholesterol and lipoproteins of very low-density lipoprotein (VLDL) in plasma. Therefore, these compounds incorporated in foods are considered functional, since its bioactive potential could be used to prevent cardiovascular disease.