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description Journal article public Indonesian Journal of Infectious Disease

Pencegahan Ventilator-associated Pneumonia dengan Pemberian Profilaksis Stress Ulcers

Adinta Anandani
Published 2015

Abstract

Ventilator-associated pneumonia (VAP) is pneumonia that occurs more than 48 hours after endotracheal intubation due to microorganisms that enter the lower respiratory tract by aspiration of secretions oropharynx derived from endemic bacteria in the digestive tract or pathogen exogenous obtained from contaminated devices or health workers. Therapy using proton pump inhibitors as prophylaxis against stress ulcer (PSU) which may be incurred as a result of the use of a mechanical ventilator may be associated with an increased risk of hospital acquired pneumonia (HAP). Based on comparative data from several randomized studies IDSA (2005) recommends the use of sucralfate compared with H2-blockers in the PSU to reduce the likelihood of onset VAP.

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