Nickel is one kind of a very important metal used for modern infrastructure, so the exploration of nickel deposits conducted continuesly to meet the needs of nickel around the world. Indonesia is a country with very large nickel deposits, ie 16,200 kt of nickel. One of the locations in Indonesia which has a nickel content is Central Halmahera. Lateric bijih containing nickel was mined from the earth to be processed and produced nickel bijih. Nickel mining has many negative environment impacts, one of them is air quality decrease due to increased concentration of air pollutants. Various types of pollutants are emitted from mining activities, such as particulates, NOx, SO2, SO3+H2SO4, nickel dust, and H2S. The contribution of air pollution from nickel mining can be found by estimate the emissions rate from mining operations. Emission rate of the nickel mining can be obtained through emission inventory. The emission source of the activities and processes in nickel mining has to be identified first in the first stages of emission inventory. Furthermore, the estimation of emissions is conducted based on the availability of obtained data. The chosen emission factor in the estimation of emissions considers the availability of data. Emissions are calculated by multiplying the emission factor with activity data. Based on the result of emission inventory, the most pollutants emitted from nickel mining is particulate. Total amount of particulate emission is 35,173.96 tonnes. Main source of particulate is ore mining with contribution of 83%. Meanwhile, the most emitted gas from nickel mining is SO2 with the amount of 8,392.61 tons.Main source of SO2 is acid plant with contribution of 72%.