The effects of peak performance nutrient (PPN) in combination with different fertilizer doses on soil properties and nutrient uptake by rice were investigated in a field experiment from seedling to maturity during the period of July to November 2014 in T. aman season. The experiment comprised of twelve treatments laid out in a randomized complete block design with three replications. The treatments were: T1: Control (no fertilizer and no PPN), T2: 100 % recommended dose of NPK, T3: 100 % NPK + PPN, T4:0 % RD +PPN only, T5: 75 % N + 100 % PK+PPN, T6: 50 % N + 100 % PK+PPN, T7: 75 % P+100 % NK + PPN, T8: 50 %P + 100 % NK + PPN, T9: 75 % K+ 100 % NP + PPN, T10: 50 % K + 100 % NP + PPN, T11:75 % NPK+ PPN, T12: 50% NPK+PPN. Experimental results reveal that the highest nutrient uptake (N and K) uptake by rice grain and straw was recorded in the treatment T7. However, P uptake by rice grain and straw were higher in treatment T3 that was statistically similar with treatment T7. Initial and postharvest soil sample analysis indicated that most of the studied soil properties including soil pH and organic matter contents were increased in T7. Therefore, the treatment combination PPN along with 75 % P+100 % NK (T7) was found to be more suitable compared to other treatment combinations for improving soil quality as well as enhancing nutrient uptake by rice. Thus peak performance nutrient (PPN) showed a positive response both on improvement of soil health as well as nutrient uptake by the crop.