The purpose of this study was to determine the differences in the average level of pain in preschoolers who were infused after being given music therapy and video game therapy at Bhayangkara TK III Hospital in Bengkulu city. This research is a quantitative study. This type of research is quasy experimental research with post test only control group approach, which is a study that did not take measurements before intervention. Measurements were only carried out after intervention, with 24 respondents taken in 2 groups, namely music therapy. and video game therapy. Data collection instruments used to measure pain with wong baker face pain rating scale. Data analysis using t-test The results of the study were that there were significant differences in the level of pain in preschoolers who were infused before and after being given music therapy and video game therapy. It is expected that nurses will apply music therapy and video game therapy as a technique for transferring pain to children. Keywords: Preschool, Video Game, Music, Pain Level.