The schools and or students number compared with the experimental laboratories was still not proportional. The available virtual laboratory media had not accommodated the anywhere and anytime learning mobility. This research was to develop mobile V-Lab for senior high school. This research and development was conducted along May December 2016. It started from identifying problems, analyzing needs, designing mobile V-Lab, producing the applications, implementing and evaluating them. Instruments used were closed and opened quessionaires, observation sheet, and interview sheet. From the data identified, it was needed an offine mobile V-Lab with simulation format, and completed with an experiment sheet. Information and perform/ experiment features linked with the downloadable experiment sheet was designed. Two prototypes were developed by using Unity and implemented in web www.m-edukasi.kemdikbud.go.id dan google play. Those, then, were evaluated and revised to get a qualified applications and implemented. Considering the results, it was recommended to make more apps.