The most important processes that ensure the functioning of biological systems and their interaction with the outside world are specific processes of recognition of each other by molecules and cells. Lectins, interacting with glycol conjugates, are directly involved in various processes of inter - and intracellular recognition. Interest in endogenous lectins is related to their ability to activate the complement system, inactivate bacteria and viruses, and regulate the process of cell adhesion in inflammatory processes and metastasis. Galectins isolated from the kidneys, liver, and brain of animals, as well as collectins of hepatocytes, are most fully characterized.