Several plants are there which are absolutely unknown to the world but have enormous medical values in curing certain diseases. This paper aims to identify the medicinal values and importance of some of those plants which can cure some diseases which are chronic as well as can be difficult to be cured in certain cases. Four such plants, viz., Alangium salvifolium, Argyriea nervosa, Hygrophila auriculata and Oroxylum indicum are chosen to detect their pharmacological values against certain diseases alongside their ayurvedic, ethnobotanical and traditional values. Their pharmacognostical characteristics are also discussed and the phytochemicals which are so far investigated by certain studies are also been discussed. Molecular studies such as docking, LC-MS, GC-MS detections of biochemical compounds are also discussed in this paper. It is seen that every plants have certain ayurvedic uses as each parts of these plants can be applied tropically or may be used as decoctions or as pastes or can be orally consumed to cure diseases. Pharmacognostical studies reveal the microscopic, macroscopic as well as the other physical factors of different plant parts. Pharmacologically these plants in certain doses are capable of curing arthritis, inflammations, sometimes can be used as anti-cancer and anti-ulcerative agents and in many other diseases including diabetes. LC-MS, GC-MS studies and other studies revealed the presence of certain phytochemicals and biochemical compounds such as flavonoids, fatty acids, esters of fatty acids, carbohydrates, amino acids and several other compounds. This paper also aims to find out the future scopes of research on these plants where scientists can work towards fulfilling it for betterment for mankind.