This study aims to determine the implementation of monitoring and evaluation (internal evaluation and evaluation) which functions as an internal audit of grant programs at the Indonesian Islamic University. The study used qualitative methods with a case study approach. Researchers chose the research location at the Indonesian Islamic University because the university had the best performance as the recipient of the best performance PKPD PHK Grant Program for the 2011-2014 period for the category of Private Higher Education / State-Owned Legal Entities. The data used is primary data. Data is obtained from documents, archive records, interviews and participant observation. Informants / speakers come from various parties who are competent to provide the information needed. This research uses credibility testing methods by extending observation, triangulation and membership. The results of this study indicate that internal monitoring and evaluation can be effective if supported by employee competencies, compensation and work culture that are built on the values of Islam that are believed.