.This study aims to develop domino media as a learning media for biology in the coordination system material for class XI SMA / MA students. The research data is in the form of media feasibility data taken from the validation results of media experts, material, language, teacher responses and student responses. Retrieval of data in this study using instruments in the form of validation questionnaires for media experts, materials, language, teacher responses and student responses. Data analysis was carried out descriptively. The validation results showed that the material expert's assessment obtained a percentage of 75 percent with proper criteria, 82.2 percent of language experts with very feasible criteria, 78 percent of media experts with proper criteria, 76.4 percent of biology teacher responses with proper criteria, and student responses amounted to 83.5 percent with very feasible criteria. The results obtained indicate that the media of dominance is suitable for use as a media for learning biology, especially the material for the coordination system for class XI SMA / MA.