— A few months ago there was Covid-19 virus outbreak by SARS-CoV-19 virus which has clinical manifestations, one of which is Anosmia. Anosmia cause patient was experienced smell's decreasing which causes psychological problems that loss of comfort and appetite. This condition may also cause imunity's decreasing in patient. Anosmia in Covid-19 patients could be temporary, if the body's immune system is maintained in good condition, one of the factors is continuing provide healthy and nutritious food intake, even though in tasteless conditions. Therefore, this article can be used as an educational material for the public, how to understand the neurobiological conditions of anosmia in Covid-19, further to avoid depressed due to loss of taste which could be lead to loss appetite.