This study aims to determine (1) the effect of learning cycle model 5E on physic student's critical thinking skills of class X, (2) determine the effect of learning styles on physic student's critical thinking skills of class X, (3) determine the interaction between learning cycle model 5E and learning style on physic student's critical thinking skills of class X. This research type is quasi exsperiment with research design pre-test and post-test group control design. The population this study is all student's of class X, and the sampe was selected by cluster random sampling technique and obtained X MIA 1 class as exsperiment and X MIA 3 class as control. The exsperiment class using learning cycle 5E model and control class using conventional model. The critical thinking ability's data collected by essay test that are 10 questions and the learning style ability's data collected using questionnaires that are 30 questions. Post-test data tested for naormality and homogeneity and next with hypothesis testing using analysis of variance two ways. Hypothesis test results show if sig<0,05 Ha be accepted. So that it can be concluded: (1) learning cycle 5E model take effect on physic student's critical thinking skills of class X, (2) learning style no effect on physic student's critical thinking skills of class X, (3) nothing interaction between learning cycle 5E model and learning style on physic student's critical thinking skills of class X.