Student achievement in physics lessons is low, this is due to low activity and learning readiness. Activities and learning readiness are influenced by internal and external factors such as interest and motivation. This study aims to determine the effect of learning interest and learning motivation on activities and learning readiness. This research is a type of quantitative research, with a confirmatory causal research design that aims to test the causal hypothesis. The research was conducted at SMAN 1 Sukomoro with a total population of 327 students of class X, XI and XII IPA, with a total sample of 179 students. Sampling using the Slovin formula with an accuracy level of 95% and a tolerance limit of 5%, the instrument used was a questionnaire with a Likert scale. The analysis used is descriptive analysis and SEM analysis. The results of descriptive analysis show that interest in learning, learning motivation, learning activities and student readiness are in the medium category. SEM analysis results show that learning interest has a significant effect on learning activities, learning interest has a significant effect on learning readiness, learning motivation has a significant effect on learning activities, learning motivation has a significant effect on learning readiness.