S. Malaria control program is aimed to prevent of disease transmission and treatment. The successes of malaria control program depend on many factors. One of those factors is community participation which is initially by awareness. The study which is aimed to asses relationship between knowledge and community participation was conducted in Sindangkerta village - Cipatujah Sub District - District of Tasikmalaya. This area has been high endemie malaria since malaria program was launched in southern coastal of java island. Data collection was carried out by interview to 270 respondents which was chosen as a sample. The results of th is study are 77.4% of sample is good knowledge however 13% lack participation. Base on statically test, there is not significantly relationship between knowledge and participation. This research suggested that Health District office of Tasikmalaya have to undertake facilitating and stewardship for improving community participation by local specific method and involving of key person as well.