Pepper (Piper nigrum L.) is a dimorfic plant which has ototrop and plagiotrop climbing stem. The plant was propagated vegetatively. The use of one node cutting as a seedling was widely used because it was economical for planting material. The aim of this research was to observed seedling growth and morphological variation of several numbers of cros combination of pepper. The result showed that there were variation in growth and morphological of cuttings of each cros combination either from different parents or the same parents. The growth of cros combination from the same parents incline to have equal rate. The best growth of cuttings were cros combination of LH N2xBk(1), LH4.-5-5, and LH4-5L.