In general, synthetic dyes have several advantages, among others; a variety of colors with wide color range, availability is assured, bright, stable, not easily fade, resistant to various environmental conditions, strong coloring power, easily available, cheap, economical, and easy to use. However, the use of synthetic dyes can cause health and environmental problems as well as the unfavorable impact of all forms of life. Natural dyes are non-toxic, biodegradable, and environmentally friendly. The main sources of natural dyes are plants and microorganisms, which produced a variety of colors such as; red, orange, yellow, blue, and brown. An important group of chemical compounds of natural dyes are carotenoids, flavonoids, tetrapirroles, and xantophylls. Natural dyes can be used in the textile industry, food, pharmaceutical, cosmetics, handicrafts and leather tanning. Increased concern for health and the environment to make natural dyes for coloring the main alternative to synthetic dyes, in addition to products with natural dyes have a good market.