Background: Cancer is the third leading cause of death in the world and the incidence is increase each year. In fulfilling the statistics cause of death is necessary to recorded causes of death that meets International standards and described the community data. Methods: Formulir Keterangan Penyebab Kematian (FKPK) is an instrument for recording causes of death with the criteria of the International Classification of Diseases-10 (ICD-10) recommended by World health Organization (WHO). The data collection is done by filling FKPK since January 1 to December 31, 2011 in 15 districts/cities in Indonesia. Underlying cause of death is determined based on the rules in the mortality statistics. Data classified by tabular list 1 and analyzed with SPSS. Results: Cancer cause of death in 15 districts/cities which occurred in 2011 amounted to 2433 cases. The proportion of deaths due to cancer is greater in women than in men (53.3%, 46.7%) and death at home is higher than in the hospital (62.2%, 37.8%). The highest proportion of cancer cause of death in men is hepatoma (17.5%), lung cancer (15.5%). Whereas in women is breast cancer (26.0%), cervical cancer (16.2%) and hepatoma (6.5%). The proportion cancer on children aged ≤18 years most are leukemia (44.05%). Conclusion: The incidence of cancer in Indonesia is quite high. Cancer can be prevented, it is necessary for promotive and preventive efforts to prevent cancer by applying the Clean and Healthy Behaviors and CERDIK.