Total removal is difficult to be performed in skull base tumors because its location is surrounded by important structures such as nerves and blood vessels. Therefore, radiotherapy is one of treatment modalities that has been proven efficacy. Simultaneous with the development of imaging technology and advancement of radiobiology, radiosurgery is an emerging therapeutic modality. Radiosurgery is radiotherapy method which delivers high doseirradiation in single fraction. Rational use of stereotactic radiosurgery on benign skull base tumor is from radiobiology point of view; there is no advantage can be achieved from conventional dose fractionated radiotherapy compared with high dose. However, if we want to delivered high dose radiation, we must apply rigid immobilization, target definition using stereotactic navigation and image guidance verification. Radiosurgery can only be delivered in small intracranial lesion.