Allergy and helminthiasis are having a unique relationship and more need to be studied. Helminthiasis canhave' no, positive, or negative relation with allergy. Objective of the study is to identify the relationshipbetween helminthiasis and atopic by determining human total IgE serum and identify historical recall ofallergy in childhood. This is a cross sectional study conducted on March-April 2011. The sample were 3-5grade elementary school children in Sekolah Dasar Negeri Kampung Baru sub district of Kusan Hilirdistrict of Tanah Bumbu, South Kalimantan. Stool and blood serum specimen were collected from thesamples. International Study of Asthma and Allergies in Childhood (ISSAC) questionaires wereinterviewed to their parent. Stools were checked-out through microscope by using Kato technique to foundthe worm eggs the Human total IgE serum was measured by ELISA. Results of the interview were used todetermine allergic status in children. Result showed the percentage of atopic with helminthiasis (30%) lessthan atopic without helminthiasis (48,2%). The study showed that there is a relationship between helminthinfection and allergy. It is recomended to conduct future research with larger sample and using IgE specificto explore more the relationship between helminthiasis and allergy.