Smoking is a public health problem. The health impact is related to degenerative diseases caused by smoking such as Chronic Obstructive Pulmonary Disease (COPD). WHO states that COPD is the third leading cause of death in the world. The study aims to determine the relationship between cigarette smoke exposures (active and passive) and COPD. The study design was cross-sectional. Sample was 17,246 subjects of the 2013 Basic Health Research aged> 30 years. The variables analyzed were COPD, gender, age, current smoking habit, smokers, passive smokers and former smokers. Logisticregression analysis with a complex sample to see the difference and the strength of the relationship of smoking habits and cigarette smoke exposures with a history of diagnosed COPD. The results showed a higher risk of developing COPD are in the group of smokers every day (including ex-smokers every day) with an OR of 3.73. Tobacco smoke exposures in the population who do not smoke (including passive smokers) have a significant relationship with the incidence of COPD, with OR of 1.69.