Tendon Healing After Echinacea Purpurea Intake: Histological and Biomechanical Evaluation

Adib Khumaidy
Journal article Indonesian Journal of Orthopaedics • December 2012

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(English, 6 pages)

Abstract

Introduction.Tendon injury is a major problem in sports and occupational medicine. Various methods have already been utilized to accelerate healing process and to allow recovery of normal mo9rphology and function of tendon. Among those is the use of herbal medicine, including Echinacea. The purpose of this study was to evaluate effect of echinacea on tendon healing through histological and biomechanical evaluation. Material and Methods.This is an experimental study with post-test only control group design. Thirty male white rats were included in the study and have their Achilles tendon injured and repaired. They were randomly allocated into 6 groups. Three groups received 15 mg echinachea, while the others three served as control. One group from echinachea and control group were sacrificed at week-2, -4, and -6 for histological evaluation using Bonar score. Biomechanical test was also performed at week-6. Results.In biomechanical test, force required to rupture echinachea and control group was 49.68±6.73 and 30.8±1.04 N (p=0.003). In histological evaluation at week-6, tenocyte and collagen score between each group varied significantly (p=0.003 and p=0.005 respectively). At week-4, tenocyte score between each group varied significantly (p=0.004). The collagen score between each group also varied significantly (p=0.031). There was no difference in Bonar score between each group at week-2. Conclusions. Echinacea gives tendon healing a better biomechanical property as well as higher tenocyte and collagen score. The higher scores are obvious after week-4.

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Indonesian Journal of Orthopaedics

The Indonesian Journal of Orthopaedics is published quarterly by the Indonesian Orthopaedic Assoc... see more